Cell Screening Intern

Summer Internship – Cell Screening and Pharmacology, Discovery Technology

Position

We are seeking a highly skilled and motivated Summer Intern with expertise in cell-based screening assays to join Nurix’s Research team. Nurix is devoted to unlocking the therapeutic potential of the ubiquitin proteasome system (UPS) in oncology, immune-oncology and other therapeutic areas. The successful candidate will be an integral member of the research team responsible for developing an independent project. In addition, the candidate will be expected to culture cells, execute cellular assay screens and perform pharmacological characterization experiments. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic team environment.

Responsibilities

• Perform routine mammalian cell and tissue culture including thawing, expansion, banking, and recovery of multiple engineered cell lines under aseptic conditions.
• Perform cellular assays and screenings to evaluate protein modulation using cutting-edge technologies and automated workflows.
• Independently execute basic lab math to support assay setup (serial dilutions and seeding density calculations) and ensure accurate reagent preparation for high‑throughput screens.
• Execute experimental protocols for assays related to cellular UPS (Ubiquitin-Proteasome System) for targeted protein degrader identification and optimization. 
• Analyze experimental data, troubleshoot technical challenges, and propose innovative solutions.
• Keep accurate and detailed records of experiments, methodologies, and results in electronic laboratory notebooks and database.
• Present findings at internal meetings and contribute to scientific discussions to drive project advancement.

Qualifications

• Current undergraduate or BS in a relevant scientific field (Pharmacology, Biology, etc.) with a strong academic track record. 
• Hands-on experience with mammalian cell culture and ability to independently execute, analyze, and report results of quantitative plate-based cellular assays (e.g. luminescence assays)
• Exceptional analytical and problem-solving skills.
• Impeccable organizational skills and an unwavering attention to detail, readily adaptable to the demands of a dynamic research environment.
• Excellent communication skills, fostering collaboration and teamwork within a diverse and multidisciplinary setting.

Intern’s Supervisor: Dipna Venkatachalam

Duration of Internship: June 1st – September 30th

Anticipated hours of work/week: 40 hours/week (in person)

Location: Office/Lab at 1600 Sierra Point Pkwy, Brisbane, CA 94005