Discovery Biology Intern

Nurix Therapeutics is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing targeted protein degradation medicines to improve treatment options for patients with cancer and inflammatory diseases. We are seeking a highly motivated summer intern to join our Discovery Biology research team to support targeted protein degradation projects by performing cell culture and executing cell-based assays in a collaborative, fast-paced environment. This internship is designed to provide hands-on laboratory experience, exposure to modern drug discovery, and the opportunity to contribute meaningful data to ongoing research programs under the guidance of an experienced scientist.

Supervisor: Caroline Davis | LinkedIn

Expected duration: June 1 – September 25, 2026 (start and end dates flexible)

Anticipated weekly hours: 40 hours per week, on-site

Responsibilities

• Perform experiments under the guidance of an experienced scientist, following established protocols and contributing to troubleshooting and refinement of experimental workflows.
• Culture and maintain immortalized mammalian cell lines, ensuring consistent cell health and quality for downstream assays.
• Perform standard cell biology techniques (e.g., Western blotting, microscopy, flow cytometry, RT-qPCR) to evaluate compound activity in cells.
• Assist in the design, development, and optimization of cell-based assays and assess functional outcomes of small molecules and degraders.
• Maintain accurate, well-organized, and up-to-date electronic laboratory notebooks (ELNs), documenting experimental methods, results, and interpretations in a clear and reproducible manner.
• Summarize and communicate experimental findings to the supervising scientist during regular check-ins and relevant subgroup meetings.
• Prepare and deliver an end-of-summer presentation summarizing project objectives, methods, results, and key learnings to the broader department team.
• Adhere to all laboratory safety policies, standard operating procedures, and good documentation practices.

Minimum Qualifications 

• Current or recent undergraduate student in Biology, Biochemistry, Molecular Biology, Immunology, Pharmacology, Bioengineering, or a related life science field.
• Completed foundational coursework in cell biology, molecular biology, and/or biochemistry.
• Some prior wet-lab experience from coursework, research, or a prior internship (e.g., pipetting, solution preparation, basic cell or molecular biology techniques).
• Ability to commit to a full-time, on-site internship for the duration of the summer program.

Preferred Qualifications

• Hands-on experience with mammalian cell culture, including routine passaging and basic aseptic technique.
• Exposure to one or more of the following techniques: Western blotting, fluorescence microscopy, flow cytometry, or RT-qPCR.
• Strong attention to detail, good record‑keeping habits, and interest in targeted protein degradation or E3 ligase biology.

What you’ll gain

• Hands-on experience in mammalian cell culture and core cell biology techniques, exposure to industry drug discovery in targeted protein degradation, and mentorship from scientists on a collaborative research team.