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Postdoctoral Researcher in Kidney cancer program

UT Southwestern Medical Center
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Description

WHY UT SOUTHWESTERN? 

With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

The Kidney Center Program (KCP) in the Department of Internal Medicine is seeking a highly motivated Postdoctoral Researcher to join our team. KCP's mission is to improve the lives of individuals affected by renal cell carcinoma (RCC) through rigorous scientific research and compassionate care. Our current projects focus on identifying early diagnostic biomarkers for various RCC subtypes and discovering therapeutic targets to enhance patient treatment.

The laboratory maintains one of the largest collections of patient-derived xenograft (PDX) models and transgenic animal models, integrating bioinformatics approaches to investigate tumorigenesis within the tumor microenvironment. Our goal is to understand how divergent signaling mechanisms contribute to RCC progression and to develop therapeutic strategies that improve patient outcomes.

 

BENEFITS 

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include: 

- PPO medical plan, available day one at no cost for full-time employee-only coverage 

- 100% coverage for preventive healthcare-no copay 

- Paid Time Off, available day one 

- Retirement Programs through the Teacher Retirement System of Texas (TRS) 

- Paid Parental Leave Benefit 

- Wellness programs 

- Tuition Reimbursement 

- Public Service Loan Forgiveness (PSLF) Qualified Employer 

- Learn more about these and other UTSW employee benefits!

Experience and Education   

  • Ph.D. in Computer Science or a related field of biological science, thesis work in bioinformatics and computational biology.   
  • Strong expertise in NGS data analysis and bioinformatics pipeline development.
  • Proficiency in programming languages such as Python, R, or Perl, as well as experience working with HPC environments.
  • Experience with single-cell sequencing, multi-omics data integration and machine learning is highly desirable.
  • Experience with electronic medical records (EMR) and cancer research is preferred but not required.
  • Excellent analytical, problem-solving, and organizational skills.
  • Strong publication record and ability to work independently while contributing to a collaborative research environment.

 

Job Duties   

  • Lead and coordinate research projects, either independently or as part of a larger research initiative, applying expertise in molecular biology, genetics, and computational methods.
  • Develop and manage state-of-the-art analytic pipelines for single-cell sequencing and next-generation sequencing (NGS) datasets (including WGS, WES, RNA-seq, ATAC-seq, and ChIP-seq).
  • Perform complex data analysis using advanced computational and bioinformatics techniques, leveraging high-performance computing (HPC) clusters.
  • Design and implement software solutions to support new and ongoing research projects.
  • Oversee the development and maintenance of clinical and research databases, ensuring efficient data management for ongoing studies.
  • Prepare research reports, present findings at scientific meetings, and contribute to manuscript preparation for peer-reviewed publications.
  • Provide guidance on bioinformatics methodologies and computational workflows to support the research team.
  • Collaborate with interdisciplinary teams, including clinicians, computational biologists, and experimental scientists, to drive translational research initiatives.

 

This position offers a unique opportunity to work at the intersection of computational biology and translational cancer research, contributing to impactful discoveries in RCC.

Perform other duties as assigned.           

**Other Duties:  Performs other duties as assigned.   

SECURITY AND EEO STATEMENT 

Security This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

EEO statement

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; sex; including sexual harassment; age; disability; genetic information; citizenship status; and protected veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression.